In Figure 4 A, the switching of pH contributes to a highly significant increase in observed DPV peak current for both active, pH-responsive zippers and control zipper-modified electrodes when supported by a phosphate/Tris buffer system ( p < 0.0001 for both).
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Probing the Conformational States of a pH-Sensitive DNA Origami Zipper via Label-Free Electrochemical Methods.
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