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Real-World Clinical Experience on the Usage of High-Dose Metformin (1500-2500 mg/day) in Type 2 Diabetes Management.

Clin Med Insights Endocrinol Diabetes · 2021 · PMC8280839 · PMID 34345194

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an increasing trendno p-value reported
Also, an increasing trend was observed in the duration of high-dose metformin therapy according to the increased levels of HbA1c indicating an association between poor glycaemic control and longer duration of metformin therapy.

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