An enveloped virus-like particle vaccine expressing a stabilized prefusion form of the SARS-CoV-2 spike protein elicits highly potent immunity.

Vaccine · 2021 · PMC8282453 · PMID 34304928

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highly significantp = 0001a dropped decimal point

At 3dpi, two doses of VBI-2902a resulted in highly significant (p = 0001) viral load median reductions ( Fig. 8 a) of 4,45 Log10 (IQR 4,95–4,33)in the cranial lobe and 5,17 Log10 (IQR 5,69–4,39) in the caudal lobe relative to non-immunized animals.

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