Evaluation of economic burden with biologic treatments in Crohn's disease patients: A mirror image study using an insurance database in Japan.

PLoS One · 2021 · PMC8289035 · PMID 34280242

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a decreasing trendno p-value reported

Extended follow-up showed a decreasing trend in HRU and costs till 24 months but an increase after 36 months.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.