Review of the treatment options for epilepsy in tuberous sclerosis complex: towards precision medicine.

74 In a subgroup analysis of Japanese patients in the EXIST-3 study, a positive trend towards an improvement of autism spectrum disorder symptoms, evaluated using the Pervasive Developmental Disorders Autism Society Japan Rating Scale, was observed. 73 In contrast, two RCTs have failed to demonstrate significant differences between EVE and placebo with regard to a wide range of

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