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LncRNA CASC2 is involved in the development of chronic obstructive pulmonary disease <i>via</i> targeting miR-18a-5p/IGF1 axis.

Ther Adv Respir Dis · 2021 · PMC8290508 · PMID 34266334

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a decreasing trendno p-value reported
10 In the serum of sepsis patients, CASC2 shows a decreasing trend compared with that in healthy controls. 24 CASC2 can inhibit the secretion of inflammatory cytokines in LPS-stimulated human renal tubular epithelial HK‐2 cells. 24 In a study of ALI, CASC2 is reported to attenuate LPS-induced inflammatory response in ALI cell models. 10 Therefore, in the current study, we further explored the role of CASC2 in the inflammatory response, and the levels of several inflammatory cytokines were measured.

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