Mechanisms underlying neonate-specific metabolic effects of volatile anesthetics.

Pairwise comparisons of isoflurane- and control-exposed animals demonstrates highly significant reductions in β-HB in the isoflurane-exposed group at each timepoint ( Figure 1D ). 1.5% isoflurane also led to a significant increase in lactate by 60 min (see Figure 1—figure supplement 1 ; see also ETC CI).

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