Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients.

Cell Rep · 2021 · PMC8299183 · PMID 34352226

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highly significantno p-value reported

After the 1 st vaccination, the 58 naive vaccine recipients showed a highly significant but transient increase of IFN-γ (∼2.5×; Figure 2 A), IP-10/CXCL10 (∼2×; Figure 2 B), and IL-6 (1.5×; Figure 2 C) at day 2 followed by rapid downregulation close to baseline levels by day 8.

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