Barely Significant
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Continual Decline in Azole Susceptibility Rates in <i>Candida tropicalis</i> Over a 9-Year Period in China.

Front Microbiol · 2021 · PMC8299486 · PMID 34305872

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an increasing trendno p-value reported
Although it was notable to find that a greater proportion of isolates from blood cultures were resistant to azoles than those from other clinical specimens (27.2 versus 17.6% for fluconazole and 25.6 versus 15.4% for voriconazole, respectively), there was also an increasing trend in the rate of resistance during the 9-year period.

also in 63,971 other papers

a worrying trendno p-value reported
Emergence of echinocandin- and multidrug-resistant isolates was also noted and is a worrying trend needing further scrutiny so that urgent efforts can be directed at arresting the trend.

also in 642 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.