LncRNAs Associated with Neuronal Development and Oncogenesis Are Deregulated in SOD1-G93A Murine Model of Amyotrophic Lateral Sclerosis.

An interesting trend was found in the thoracic and lumbar spinal cord, where the lncRNA decreased in WT mice, but increased in SOD1-G93A mice ( Figure 6 C).

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There is a significant decrease in WT mice from 8 to 18 weeks of age in the cerebellum and prefrontal cortex, and this decrease is extremely significant and present also in the SOD1-G93A mice in the hippocampus area ( Figure 3 C).

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