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A Novel Radiographic Measurement Method for the Evaluation of Metatarsophalangeal Joint Dislocation of the Lesser Toe in Patients with Rheumatoid Arthritis.

Int J Environ Res Public Health · 2021 · PMC8303857 · PMID 34299970

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a decreasing trendno p-value reported
A decreasing trend in disease activity among patients who underwent orthopedic surgeries was also reported [ 8 ].

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an increasing trendno p-value reported
The IORRA cohort [ 7 ], one of the largest registries in Japan, reported an improvement in disease activity, a decreasing number of surgeries with the widespread use of bDMARDs, and an increasing trend in arthroplasties.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.