Barely Significant
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Pharmacokinetic Comparison between Methotrexate-Loaded Nanoparticles and Nanoemulsions as Hard- and Soft-Type Nanoformulations: A Population Pharmacokinetic Modeling Approach.

Pharmaceutics · 2021 · PMC8309067 · PMID 34371740

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may be significantno p-value reported
These pharmacokinetic comparison results suggest that there may be significant pharmacokinetic differences between methotrexate-loaded nanoparticles and nanoemulsions. 3.2.

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