Barely Significant
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Monoclonal Antibodies Targeting an <i>Opisthorchis viverrini</i> Extracellular Vesicle Tetraspanin Protect Hamsters against Challenge Infection.

Vaccines (Basel) · 2021 · PMC8310160 · PMID 34358156

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highly significantno p-value reported
viverrini infection, we raised two monoclonal antibodies (mAbs) to recombinant Ov -TSP-2-LEL, both of which significantly blocked the uptake of Ov -EVs by human cholangiocytes in vitro, and one of which, after passive transfer to hamsters, conferred highly significant protection against challenge infection with O. viverrini compared to a control mAb. 2.

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