Barely Significant
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Comparison of efficacy of gabapentin and memantine premedication in laparoscopic cholecystectomies for postoperative pain relief - A randomised placebo controlled trial.

Indian J Anaesth · 2021 · PMC8312383 · PMID 34321685

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a decreasing trendno p-value reported
Memantine can be used in doses starting from 5 mg to 30 mg with a gradual increase over a week, and we used 20 mg for this study as per a previous study.[ 6 ] The NRS score showed a decreasing trend in all the three groups over 2 and 4 h post-operatively and was statistically insignificant.

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