The Co-occurrence of Chronic Hepatitis B and Fibrosis Is Associated With a Decrease in Hepatic Global DNA Methylation Levels in Patients With Non-alcoholic Fatty Liver Disease.

Front Genet · 2021 · PMC8318039 · PMID 34335686

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a decreasing trendno p-value reported

The global DNA methylation levels showed a decreasing trend in the presence of co-occurrent CHB and inflammation progression ( P trend = 0.011), co-occurrent CHB and presence of fibrosis ( P trend = 0.007), and co-occurrent CHB and NAFLD progression ( P trend = 0.035).

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