Neutrophil-to-lymphocyte ratio and outcomes in patients with new-onset or worsening heart failure with reduced and preserved ejection fraction.

There was no significant interaction between NLR and LVEF category (<40% or ≥40%) for the association with the primary outcome ( P = 0.06) or mortality ( P = 0.27), with NLR significantly associated with the primary outcome in patients with LVEF < 40% (HR 1.24; 95% CI 1.12–1.35, P < 0.001), though the association did not quite reach statistical significance in patients with LVEF ≥40% (HR 1.10; 95% CI 0.99–1.23, P = 0.07).

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