Sexual dimorphism of monocyte transcriptome in individuals with chronic low-grade inflammation.

Biol Sex Differ · 2021 · PMC8320037 · PMID 34321081

Europe PMC DOI

hedged sentence

0.0098

closest p · 0.2× alpha

0.0098

boldest claim

The sentences

borderline significance-log( p ) = 2.01actually significant

In addition to the 11 significant female-biased pathways, we identified two male-biased pathways with borderline significance: pathways related to programmed cell death protein 1 (PD-1), programmed cell death-ligand1 (PD-L1) cancer immunotherapy (z-score = − 0.82, -log( p ) = 2.01) and p53 signaling (z-score = − 0.45, -log( p ) = 1.64).

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