Barely Significant
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From reaction kinetics to dementia: A simple dimer model of Alzheimer's disease etiology.

PLoS Comput Biol · 2021 · PMC8321409 · PMID 34280181

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highly significantno p-value reported
For example, the ratio of monomer production to monomer clearance, S / κ , is a term that is highly significant, suggesting that its reduction would lessen disease risk and slow progression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.