Firstly, it was found that annexin a1 expression showed an increasing trend over a three-month period at both mRNA and protein level, while the expression of miR221 exhibited a decreasing trend, showing a negative correlation between the two molecules (Fig. 2 a).
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miR221 regulates cell migration by targeting annexin a1 expression in human mesothelial MeT-5A cells neoplastic-like transformed by multi-walled carbon nanotube.
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