A machine learning case-control classifier for schizophrenia based on DNA methylation in blood.

The highly significant enrichment of SZ GWAS SNPs in the vicinity of CpG probes identified by our model (Fig. 5C ) and the finding that leukocyte subtype is not an important variable in our model (Table 3 ) are also inconsistent with simple confounding by medication effects on the blood methylation profile.

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