Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent.

Front Pharmacol · 2021 · PMC8329483 · PMID 34354587

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may be significantno p-value reported

Overall, while expression of the protein and mRNA transcripts of CES1 is highest in the liver, the high expression in other tissues, including lung, suggests that extra-hepatic esterase metabolism of remimazolam (to CNS 7054) may be significant.

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