The cost of equipment acquisition generally rises with increasing size; however, at large scale, this cost tends to stabilize (i.e., the cost difference between a 10 L and a 20 L bioreactor is proportionally greater than the difference between a 110 L and a 120 L bioreactor), causing the impact of production scale to be highly significant.
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Comparative Economic Analysis Between Endogenous and Recombinant Production of Hyaluronic Acid.
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