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The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.

Sci Adv · 2021 · PMC8336962 · PMID 34348895

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a positive trendno p-value reported
A closer inspection of the RNA metabolism gene signature uncovered a positive trend for genes associated with rRNA processing [e.g., small subunit (SSU) components DHX37 , UTP3 , EXOSC4 , and RRP9 ], while genes regulating RNA nuclear transport were found mostly down-regulated ( Fig. 3, D and E , and table S2C).

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