Clinical Research on the Mechanisms Underlying Immune Checkpoints and Tumor Metastasis.

Front Oncol · 2021 · PMC8339928 · PMID 34367975

Europe PMC DOI

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might not be significantno p-value reported

Thus, CTLA-4 may play a role in tumor metastasis, especially that of CRC, by affecting immune cell function and cytokine secretion, but this role might not be significant in other tumors, as it may be masked by some unknown factors.

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