Compared to the control group, an increasing trend of autophagosomes (green signals in MDC staining) were noted in the glutamate-treated group; ST2-104 peptide decreased the number of autophagosomes (Fig. 6 a).
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Inhibition of autophagy by CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR pathway contributes to ischemic postconditioning-induced neuroprotection against cerebral ischemia-reperfusion injury.
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