Distinct gut microbial compositional and functional changes associated with impaired inhibitory control in patients with cirrhosis.

Several species belonging to symbionts such as Akkermansia , as well as potential SCFA producers belonging to Lachnospiraceae and Ruminococcaceae were higher in those without MHE, while the reverse was seen with potential pathobionts belonging to Proteobacteria and urease-producing Streptococcus species ( Table 2 and Table S1). MHEICT versus not : Similar to PHES, no changes in alpha-diversity was seen and PERMANOVA of borderline significance ( p = .08; Figure 3 ) was seen for beta-diversity.

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