Review of the Molecular Genetics of Basal Cell Carcinoma; Inherited Susceptibility, Somatic Mutations, and Targeted Therapeutics.

Cancers (Basel) · 2021 · PMC8345475 · PMID 34359772

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp = 2.2 × 10 −20actually significant

Gene Polymorphisms Affecting Tumor Suppressor Proteins A polymorphism, rs78378222, in TP53 , which encodes the tumor suppressor TP53 gene, is highly significant for BCC, with an overall OR of 2.16 (95% CI 1.83–2.54; p = 2.2 × 10 −20 ).

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