Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination.

However, for both PV and VM neurons there were more well-myelinated axons below the identity line, suggesting that there was a slight trend toward loss of myelin after recovery (ΔPLM for axons with >75% PLM at baseline, PV: median: –6%, range: [–82%, 15%]; VM: median: –8%, range: [–90%, 10%]) (Fig. 5e, f ).

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