Changes in Quantity of Opioids Dispensed following Florida's Restriction Law for Acute Pain Prescriptions.

Change in Morphine Milligram Equivalents Prior to HB21, there was a decreasing trend in MMEs per day (rate of −.09 MMEs per study month, 95% CI −.16, −.04 MMEs per study month) ( P = .002) with a mean MMEs per day of 34.7 for all opioids during the study period; following implementation there was a non-significant increase in MMEs for all opioids to 37.4 (change of 2.69 MMEs, 95% CI −.51, 5.89 MMEs) ( P = .105) ( Table 1 ; Figure 2 ).

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