highly significantp < 0.001
The correlation between PFO and ischemia lesion incidence Due to the potential role of PFO in brain ischemia lesions, we analyzed the correlation between PFO and brain ischemia lesions in PFO and control groups and found a highly significant increase in the percentage of cases with brain ischemia lesions in the PFO group compared with the control group (p < 0.001).