Accumulating evidences indicated that inflammatory response played a key role in the pathogenesis of cerebral I/R injury, and the anti‐inflammatory treatment might be significant in ischaemic stroke. 42 , 43 , 44 Pro‐inflammatory cytokines could not only damage peripheral neural cells, but destroy the permeability of the blood brain barrier which would aggravate the cerebral oedema and further cause brain damage after an ischaemic stroke. 45 , 46 , 47 In accordance with previous reports, 48 , 49 we found that the release of pro‐inflammatory cytokines increased the cerebral I/R injury in mice.
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Dental pulp stem cell-derived exosomes alleviate cerebral ischaemia-reperfusion injury through suppressing inflammatory response.
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