A systematic review, published in 2013, retrieved 23 studies (on total 1,064 patients) in which a multivariable analysis for prognostic factors for survival of patients with metastatic NSCLC and up to five metastases showed that N-stage was a highly significant prognostic factor ( 25 ).
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Defining oligometastatic non-small cell lung cancer: concept versus biology, a literature review.
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