Impact of long-term doxycycline on lung function & exacerbations: A real-world open, prospective pilot observation on chronic obstructive pulmonary disease.

The available repeat spirometry in some of these patients (n=7 for each group) revealed that the patients who had consumed doxycycline even for a relatively short duration (141.3±110.9 days) as an add-on had an overall trend of improvement with a lesser decline in spirometric variables compared to those who remained on COPD treatment alone beyond the point of dropout ( Table V ).

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