Barely Significant
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Targeting Some Enzymes with Repurposing Approved Pharmaceutical Drugs for Expeditious Antiviral Approaches Against Newer Strains of COVID-19.

AAPS PharmSciTech · 2021 · PMC8354522 · PMID 34378108

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highly significantno p-value reported
Above all, viral infections are arduous to cure due to the inherent mutating nature of their genomes, as well as quick development of resistance to human immunological systems and the administered antivirals, for which those unseen particles pose a highly significant hazard to humanity, everywhere.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.