Trace element profile and incidence of type 2 diabetes, cardiovascular disease and colorectal cancer: results from the EPIC-Potsdam cohort study.

Eur J Nutr · 2021 · PMC8354864 · PMID 33590281

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After adjustments for age, sex, education and established risk factors, higher concentrations of SELENOP and Se-to-Cu ratio were associated with a lower risk of developing CRC (HR per SD, 95% CI 0.80, 0.71–0.90 and 0.77, 0.65–0.92, respectively), while Free Zn was observed to associate with borderline significance with increased risk of CRC (HR per SD, 95% CI 1.17, 1.00–1.38) (Fig. 2 ).

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