almost significantP = 6.66 E-10
Moreover, patients with genotype TC were likely to have higher age-at-onset migraine than patients with the wild type. Associations in the subgroups with aura In all migraine cohorts with aura, 3 SNPs had P < 5 E-08 (rs77630941 in CUX1 , rs146778855 in CDH18 , and rs117608715 in NOL3 ) and 1 SNP (rs150592309 in PRAP1 ) were almost significant in the aura groups ( P = 6.66 E-10, P = 1.21 E-08, P = 1.78 E-08, P = 8.88 E-08, respectively in Fig. 4 A–D).