Looking for pathways related to COVID-19: confirmation of pathogenic mechanisms by SARS-CoV-2-host interactome.

Cell Death Dis · 2021 · PMC8357963 · PMID 34385425

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highly significantno p-value reported

For KEGG database the gene enrichment analysis on interactomes of NS7b, ORF1a, ORF3a, and ORF8 showed pathway clusters highly significant and consistent with possible pathogenic mechanisms, such as the activation of the complement and of the coagulative cascade 32 , and the TGF-β-dominated immune response 33 .

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