RAPGEF2 mediates oligomeric Aβ-induced synaptic loss and cognitive dysfunction in the 3xTg-AD mouse model of Alzheimer's disease.

Neuropathol Appl Neurobiol · 2021 · PMC8359155 · PMID 33345400

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an increasing trendno p-value reported

RAPGEF2 levels in 12‐month‐old mutants also showed an increasing trend without statistical significance, possibly due to the high variability of RAPGEF2 levels in older 3xTg‐AD mice (Figure S2 ).

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