In our previous report from the EpiPath cohort, multiple correction testing during our survey of the complete immune system meant that NK cells only narrowly missed significance ( 18 ), and the only other comparable study did not investigate NK cells ( 64 , 112 ).
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Unbiased Screening Identifies Functional Differences in NK Cells After Early Life Psychosocial Stress.
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Unfortunately, in our previous report, this result was highly significant prior to, but not after, post-hoc multiple testing correction ( 18 ) The limitations of our pre-clinical study include potential litter effects and the absence of a clear HPA axis phenotype.