Overexpression of hsa_circ_0008274 inhibited the progression of lung adenocarcinoma by regulating HMGA2 via sponging miR-578.

Thorac Cancer · 2021 · PMC8364990 · PMID 34236145

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a decreasing trendno p-value reported

As previous studies have confirmed, the expression of hsa_circ_0008274 in LUAD shows a decreasing trend. 17 , 18 , 19 Our study aimed to discover that hsa_circ_0008274 expression is downregulated in LUAD tissues, and cell lines compared with normal, in vitro experiments show that overexpression of hsa_circ_0008274 inhibits the proliferation and invasion of LUAD.

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