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Deep survey for designing a vaccine against SARS-CoV-2 and its new mutations.

Biologia (Bratisl) · 2021 · PMC8369332 · PMID 34421121

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an increasing trendno p-value reported
An increasing trend is found in using TLR agonists as potential built-in adjuvants for the development of novel vaccines.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.