Incidence of lower limb amputation in people with and without diabetes: a nationwide 5-year cohort study in Japan.

BMJ Open · 2021 · PMC8372805 · PMID 34404707

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a decreasing trendno p-value reported

In detail, there was a little change among men with diabetes and a decreasing trend in women with diabetes for major amputation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.