A Literature Review of the Potential Impact of Medication on Vitamin D Status.

174 This failed to reach significance at lower doses of ICS.

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This was especially highly significant in male patients who had been prescribed severe polypharmacy. 80 A similar conclusion was reached in the study by Sohl et al, who examined these effects in two different cohorts of over 2000 elderly Dutch patients. 76 Again, the study data showed that patients prescribed more than one medication had lower concentrations of 25(OH)D in serum than non-users, leading the authors to recommend that vitamin D supplementation ought to be considered in patients prescribed long-term medication regimens.

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