Suppressed PLIN3 frequently occurs in prostate cancer, promoting docetaxel resistance via intensified autophagy, an event reversed by chloroquine.

Med Oncol · 2021 · PMC8374126 · PMID 34410522

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a decreasing trendno p-value reported

LC3A and p62 mRNA levels displayed a decreasing trend, suggesting a suppression of the autophagic flux upon exposure of the parental cells to docetaxel (Fig. 2 d).

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