Efficacy and safety of pegylated interferon-α2b in moderate COVID-19: a phase 3, randomized, comparator-controlled, open-label study.

Combining PEG IFN with steroids likely eliminated this defect by supplementing this important cytokine, leading to a highly significant improvement in RT-PCR negativity, change on the WHO ordinal scale, duration of supplemental oxygenation, as well as time to resolution of clinical signs and symptoms in comparison with those patients who received steroids but not PEG IFN.

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