Barely Significant
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Novel Approaches to Treating Relapsed and Refractory Multiple Myeloma with a Focus on Recent Approvals of Belantamab Mafodotin and Selinexor.

Clin Pharmacol · 2021 · PMC8380622 · PMID 34434061

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fairly significantno p-value reported
32 Though there is a critical need for novel therapies in this treatment space, the initial FDA approved dose and schedule of selinexor proved difficult in the clinical setting with fairly significant gastrointestinal toxicity including nausea, anorexia and weight loss.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.