SNP rs10880322 had neither a strong mean effect (GWAS p = 0.025) nor a variance effect (Levene’s test p = 0.428) on cranial base width when tested alone; however, when taking into account its interaction with rs10511683 ( FOCAD ), both the main and interaction effects of rs10880322 became highly significant ( Supplementary Table 5 and Supplementary Figure 6 ).
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<i>PRICKLE1</i> × <i>FOCAD</i> Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits.
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