Temporal and regional trends of antibiotic use in long-term aged care facilities across 39 countries, 1985-2019: Systematic review and meta-analysis.

PLoS One · 2021 · PMC8382177 · PMID 34424939

Europe PMC DOI

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a decreasing trendno p-value reported

However, this result is heavily based on estimates from Australia (six of eight studies) which show a decreasing trend in appropriateness between 2010–2018.

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an overall trendno p-value reported

Thus, though we did not detect an overall trend in antibiotic use in LTCFs, this does not preclude changes in antibiotic use rates within regions and countries over time, which our analysis was not powered to detect.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.