Adaptive Proteome Diversification by Nonsynonymous A-to-I RNA Editing in Coleoid Cephalopods.

Comparing this lower bound to the actual numbers observed, we find a highly significant suppression of these mutations, suggesting that a sizable fraction of strongly edited recoding events in coleoids are adaptive in the strong sense, namely it is beneficial to have an editable A at these positions, over both uneditable A and genomically encoded G.

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