Trends in incidence, treatment, survival and subsequent breast cancer in lobular carcinoma in situ in the Netherlands: A population-based analysis.

Breast · 2021 · PMC8382994 · PMID 34428722

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an increasing trendno p-value reported

There was an increasing trend (>50 %) towards no surgery over the last decade, which is consistent with the recommendation for active surveillance in the Dutch guidelines, but contrary to LCIS treatment in the United States, where it followed the general trend of more mastectomies [ 22 ].

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